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P H Hart Selected Research

Tea Tree Oil

1/2005Reduction of nickel-induced contact hypersensitivity reactions by topical tea tree oil in humans.
12/2002Tea tree oil reduces histamine-induced skin inflammation.
5/2002Tea tree oil reduces the swelling associated with the efferent phase of a contact hypersensitivity response.
4/2001The water-soluble components of the essential oil of Melaleuca alternifolia (tea tree oil) suppress the production of superoxide by human monocytes, but not neutrophils, activated in vitro.
11/2000Terpinen-4-ol, the main component of the essential oil of Melaleuca alternifolia (tea tree oil), suppresses inflammatory mediator production by activated human monocytes.

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P H Hart Research Topics

Disease

6Contact Dermatitis (Eczema, Contact)
03/2008 - 03/2000
4Asthma (Bronchial Asthma)
12/2011 - 04/2001
4Necrosis
03/2007 - 04/2000
4Inflammation (Inflammations)
12/2002 - 04/2001
3Hypersensitivity (Allergy)
12/2011 - 03/2000
1Type 1 Diabetes Mellitus (Autoimmune Diabetes)
03/2017
1Psoriasis (Pustulosis Palmaris et Plantaris)
09/2007
1Respiratory Hypersensitivity
09/2007
1Erythema
01/2005
1Melanoma (Melanoma, Malignant)
05/2004
1Immediate Hypersensitivity
06/2002
1Blister (Bulla)
10/2001
1Skin Neoplasms (Skin Cancer)
01/2001
1Uveitis
02/2000

Drug/Important Bio-Agent (IBA)

5Tea Tree OilIBA
01/2005 - 11/2000
4AntigensIBA
09/2007 - 03/2000
4Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2007 - 11/2000
4Histamine (Histamine Dihydrochloride)FDA Link
12/2002 - 04/2000
3Vitamin DFDA LinkGeneric
03/2017 - 03/2008
3AllergensIBA
05/2010 - 02/2003
3LipopolysaccharidesIBA
08/2001 - 02/2000
2CytokinesIBA
09/2007 - 04/2001
2InterleukinsIBA
03/2007 - 11/2000
2terpinenol-4IBA
06/2002 - 05/2002
1Biological ProductsIBA
12/2011
1OvalbuminIBA
05/2010
1calcipotriene (calcipotriol)FDA LinkGeneric
03/2008
11,25-dihydroxyvitamin DIBA
03/2008
1NF-kappa B (NF-kB)IBA
03/2007
1NF-KappaB Inhibitor alphaIBA
03/2007
1NickelIBA
01/2005
1MitogensIBA
01/2005
1Melanoma-Specific AntigensIBA
05/2004
1alpha-terpineolIBA
05/2002
1Urocanic AcidIBA
10/2001
1Neuropeptide Receptors (Neuropeptide Receptor)IBA
10/2001
1NeuropeptidesIBA
10/2001
1IgE Receptors (Fc epsilon RI)IBA
04/2001
1Interleukin-13IBA
04/2001
1Superoxides (Superoxide)IBA
04/2001
1Dinoprostone (PGE2)FDA Link
11/2000
1Interleukin-10 (Interleukin 10)IBA
11/2000
1Interleukin-8 (Interleukin 8)IBA
11/2000
1HaptensIBA
03/2000
1Interleukin-4 (Interleukin 4)IBA
03/2000
1Melanins (Melanin)IBA
02/2000
1EndotoxinsIBA
02/2000

Therapy/Procedure

1Immunomodulation
05/2004